Numerous illnesses, such as neurological problems, muscle disorders, or systemic conditions, can result in weakness in the limbs. Symptoms could include decreased coordination, inexplicable weariness, and trouble lifting or moving limbs. If you experience sudden or severe weakness, you should definitely get medical help right once. Helping the patient into a comfortable and safe position, making sure they have enough air, and preventing them from putting further strain on their weakening limbs are some examples of first aid techniques. Calling for emergency medical assistance is essential for a timely and precise diagnosis. Physicians with expertise in internal medicine, orthopaedics, or neurology may offer guidance depending on the underlying reason. It may be necessary to do diagnostic procedures like imaging scans, blood tests, or electromyography to pinpoint the precise illness causing limb weakness. For proper care and to address any potential major underlying health conditions, prompt medical action is necessary.